Enoxaparin Sodium
CAS No.: 679809-58-6 (Low molecular weight heparin)

Short Description:

Source: Extracted from the intestinal mucosa and degraded by β-elimination method.

Function and use: By inhibiting coagulation active factor X (FXa) and thrombin (FIIa), heparin pentose structure binds AT-III (antithrombin III), and exerts anticoagulant effect.
Enoxaparin sodium prevents venous thromboembolic disease (prevention of thrombosis in the veins), especially those associated with orthopaedic or general surgery; treats established deep vein thrombosis, with or without pulmonary embolism, clinical Symptoms are not severe, excluding pulmonary embolism requiring surgery or thrombolytic therapy; treatment of unstable angina pectoris and non-Q-wave myocardial infarction, in combination with aspirin; used in hemodialysis cardiopulmonary bypass to prevent thrombosis; treatment of acute ST segment Elevated myocardial infarction, combined with thrombolytics or concurrently with percutaneous coronary intervention (PCI).

Enoxaparin Sodium-Pharmacopoeia Standard: BP/EP/USP

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Indication

1. Prevention of venous thromboembolic diseases (prevention of venous thrombosis), especially in relation to orthopaedic or general surgery

2. Treatment of existing deep vein embolism, with or without pulmonary embolism, with mild clinical symptoms, excluding pulmonary embolism requiring surgery or thrombolytic therapy.

3. Treatment of unstable angina pectoris and non-Q wave myocardial infarction, combined with aspirin.

4. Used in cardiopulmonary bypass for hemodialysis to prevent thrombosis.


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