Kallidinogenase
CAS No.: 9001-01-8 (kinin-releasing activity)

Source: Extracted from porcine pancreas
Function and use:Kallidinogenase is a kind of kallikrein in human tissues and mammals. It exists in the body in the form of an inactive precursor—prekallikrein, which can degrade kininogen into kinin. Kinin can dilate blood vessels and capillaries,increase vascular permeability,improve microcirculation, regulate blood pressure, and reduce myocardial oxygen consumption. This enzyme is also an activating factor, which can activate plasminogen into plasmin, hydrolyze insoluble fibrin into soluble small peptides, thereby leading to thrombolysis, and can also regulate and reduce hypertension. For a variety of heart and cerebrovascular diseases, such as essential hypertension, arteriosclerosis, coronary atherosclerotic heart disease, cerebral arteriosclerosis, cerebral thrombosis, retinal blood supply disorders and peripheral vascular disease.

Kallidinogenase-Pharmacopoeia Standard: JP