Products
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Urokinase
CAS No. : 9039-53-6 (Plasminogen activator;fibrinolytic; enzyme)Source: Extracted from fresh male urine
Function and use: Urokinase is a fibrinolytic drug, which can hydrolyze protein, has no antigenicity, and can directly activate plasminogen. This product is mainly used for the treatment of acute myocardial infarction, acute cerebral thrombosis, cerebral vascular occlusion, peripheral arteriovenous thrombosis, central retinal vein thrombosis and other infarct diseases caused by the formation of new blood clots.Urokinase-Pharmacopoeia Standard: BP/EP/JP
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Ulinastatin
CAS No. : 80449-31-6 (Trypsin Inhibitor )Source: Extracted from fresh male urine
Function and use: Ulinastatin is a protease inhibitor with a molecular mass of 67kD, which inhibits the activities of various hydrolases such as trypsin, chymotrypsin, lactate, lipase, and hyaluronidase. It can stabilize lysosomal membrane, inhibit the production of myocardial inhibitory factors, inhibit the release of lysosomal enzymes, scavenge oxygen free radicals, inhibit the excessive release of inflammatory mediators, improve human microcirculation and tissue perfusion, and play a protective role in tissues and organs. It is an effective drug for the treatment of acute pancreatitis, chronic recurrent pancreatitis, hemorrhagic, traumatic and endotoxic shock.Ulinastatin-Pharmacopoeia Standard: CP
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Chorionic Gonadotrophin
CAS No.: 9002-61-3 (Gonadotrophic hormone)Source: Extracted from the urine of healthy pregnant women
Function and use: For women, it can promote the maturation and ovulation of follicles, and maintain the function of the corpus luteum. For men, it can stimulate the development of Leydig cells, increase androgen secretion, promote testicular descent and the development of male secondary sexual characteristics. Combined with urinary gonadotropin, it can simulate the physiological peak of luteinizing hormone and induce ovulation. Clinically, chorionic gonadotropin is still the drug of choice for the treatment of menstrual disorders, anovulatory infertility, threatened abortion and habitual live birth, cryptorchidism, and male sexual dysfunction.Chorionic Gonadotrophin-Pharmacopoeia Standard: BP/EP
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Urofollitropin
CAS No.: 97048-13-0 (Follicle-stimulating hormone)Source: Extracted from the urine of menopausal women
Function and use: Stimulate the proliferation and differentiation of granulosa cells, induce the synthesis of granulosa cell receptors, and bind to the receptors, activate the activity of enzymes in the body, promote the transformation between hormones, regulate the growth and development of human organs, sexual maturation and reproductive activities A series of related physiological processes. Regulates the menstrual cycle of women to promote follicular development and ovulation in women, regulates testicular function and gonadotropin secretion in men, and treats male infertility; it is clinically used for in vitro reproductive assistance.Urofollitropin-Pharmacopoeia Standard: BP/EP
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Menotrophin
CAS No.: 9002-68-0 (Gonadotrophin; Treatment of infertility)Source: Extracted from the urine of menopausal women
Function and use: For women, it can promote the maturation and ovulation of follicles, and maintain the function of the corpus luteum. For men, it can stimulate the development of Leydig cells, increase androgen secretion, promote testicular descent and the development of male secondary sexual characteristics. Combined with urinary gonadotropin, it can simulate the physiological peak of luteinizing hormone and induce ovulation. Clinically, chorionic gonadotropin is still the drug of choice for the treatment of menstrual disorders, anovulatory infertility, threatened abortion and habitual live birth, cryptorchidism, and male sexual dysfunction.Menotrophin-Pharmacopoeia Standard: BP
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Kallidinogenase
CAS No.: 9001-01-8 (kinin-releasing activity)Source: Extracted from porcine pancreas
Function and use:Kallidinogenase is a kind of kallikrein in human tissues and mammals. It exists in the body in the form of an inactive precursor—prekallikrein, which can degrade kininogen into kinin. Kinin can dilate blood vessels and capillaries,increase vascular permeability,improve microcirculation, regulate blood pressure, and reduce myocardial oxygen consumption. This enzyme is also an activating factor, which can activate plasminogen into plasmin, hydrolyze insoluble fibrin into soluble small peptides, thereby leading to thrombolysis, and can also regulate and reduce hypertension. For a variety of heart and cerebrovascular diseases, such as essential hypertension, arteriosclerosis, coronary atherosclerotic heart disease, cerebral arteriosclerosis, cerebral thrombosis, retinal blood supply disorders and peripheral vascular disease.Kallidinogenase-Pharmacopoeia Standard: JP
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Heparin Sodium
CAS No.: 9041-08-1 (Anticoagulant)Source: Extracted from pig intestinal mucosa
Function and use: It is an anticoagulant. It affects many aspects of the coagulation process and can prolong the coagulation time and prothrombin time. This product has rapid anticoagulant effect both in vivo and in vitro. It mainly acts on the formation of fibrin and can also reduce platelet aggregation. For the prevention and treatment of thromboembolic diseases, such as myocardial infarction, pulmonary embolism, cerebrovascular embolism, peripheral venous thrombosis, etc., it can prevent the formation and expansion of thrombus. It can also be used in the early stage of DIC and other anticoagulation in vitro and in vivo. Early application can prevent depletion of fibrinogen and coagulation factors. It can also be used as an anticoagulant in vitro instead of citrate during blood transfusion or during cardiopulmonary bypass.Heparin Sodium-Pharmacopoeia Standard: BP/EP
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Nadroparin Calcium
CAS No.: 37270-89-6 (Low molecular weight heparin)Source: extracted from pig intestinal mucosa, degraded by sodium nitrite, and obtained after calcium transfer.
Function and use: Nadroparin calcium is a low molecular weight heparin, which is depolymerized from unfractionated heparin with antithrombotic and anticoagulant effects; it has high anticoagulant factor Xa activity and low anticoagulant Factor IIa or antithrombin activity. In surgery, for the prevention of venous thromboembolic disease in situations of high or high risk of venous thrombosis; for the treatment of established deep vein thrombosis; in combination with aspirin for the acute treatment of unstable angina and non-Q-wave myocardial infarction ; Prevention of clot formation in extracorporeal circulation during hemodialysis.Nadroparin Calcium-Pharmacopoeia Standard: EP
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Enoxaparin Sodium
CAS No.: 679809-58-6 (Low molecular weight heparin)Source: Extracted from porcine intestinal mucosa and degraded by β-elimination method.
Function and use: By inhibiting coagulation active factor X (FXa) and thrombin (FIIa), heparin pentose structure binds AT-III (antithrombin III), and exerts anticoagulant effect.
Enoxaparin sodium prevents venous thromboembolic disease (prevention of thrombosis in the veins), especially those associated with orthopaedic or general surgery; treats established deep vein thrombosis, with or without pulmonary embolism, clinical Symptoms are not severe, excluding pulmonary embolism requiring surgery or thrombolytic therapy; treatment of unstable angina pectoris and non-Q-wave myocardial infarction, in combination with aspirin; used in hemodialysis cardiopulmonary bypass to prevent thrombosis; treatment of acute ST segment Elevated myocardial infarction, combined with thrombolytics or concurrently with percutaneous coronary intervention (PCI).Enoxaparin Sodium-Pharmacopoeia Standard: BP/EP
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Dalteparin Sodium
CAS No.: 9041-08-1 (Low molecular weight heparin)Source: Extracted from porcine intestinal mucosa and degraded by sodium nitrite.
Function and use: Dalteparin sodium is a low molecular weight heparin sodium, which is used for anticoagulation by promoting the inhibitory effect of antithrombin on coagulation factor Xa and thrombin. Dalteparin sodium mainly potentiates the inhibition of coagulation factor Xa, while slightly prolonging the activated partial thromboplastin time (APTT). For the treatment of acute deep vein thrombosis; prevention of coagulation in the extracorporeal circulation system during hemodialysis and hemofiltration in patients with acute renal failure or chronic renal insufficiency; treatment of unstable coronary artery disease such as unstable angina and non-Q Wave myocardial infarction; prevention of surgery-related thrombosis.
Dalteparin Sodium-Pharmacopoeia Standard: USP/EP
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Urokinase for injection
The product is mainly used for thrombolytic therapy of thromboembolic diseases. These include acute generalized pulmonary embolism, coronary artery embolism and myocardial infarction within 6-12 hours of chest pain, acute cerebrovascular embolism with symptoms shorter than 3-6 hours, retinal artery embolism and other peripheral artery embolism symptoms of severe skeletal vein thrombosis. It is also used to prevent thrombosis after prosthetic heart valve surgery, and to keep vascular cannulation and thoracic and pericardial drainage tubes unobstructed. Thrombolytic efficacy requires subsequent heparin anticoagulation to maintain.
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Chorionic Gonadotrophin for injection
Indications
1. Diagnosis and treatment of prepubertal cryptorchidism.
2. Male infertility caused by hypopituitarism can be combined with urogonadotropin. Long-term hypogonadotropin function. It should also be supplemented with testosterone therapy.
3. Anovulatory infertility in women caused by pituitary gonadotropin insufficiency is often combined with urogonadotrophin to promote ovulation after clomiphene treatment is ineffective.
4. Used for in vitro fertilization to obtain multiple oocytes, in combination with menotrophin.
5. Treatment of luteal insufficiency in women.
6. Functional uterine bleeding, threatened miscarriage in the first trimester, recurrent miscarriage.